Endocrine Abstracts

Background: Thyroid hormones are essential for normal development and metabolism. Their synthesis requires a normal function of thyroid follicular cells and adequate nutritional intake of iodine. Immortalized thyroid cell lines are widely used to study thyroid physiology and pathology. The best characterized and most widely used ones include the FRTL5 rat thyroid cell line and a derivative thereof, the PCCL3 cell line. A permanent human thyroid cell line is currently lacking. ...